Enhancing GATA5 expression bytransfecting with CDH-GATA5 in the Paclitaxel-treated Bel7402 andPLC/PRF/5 cells (Paclitaxel+CDH-GATA5 group), showed that pore migrationcapacity of the HCC cells was decreased compared to the cells transfected with the CDHempty vector (Paclitaxel+CDH group, Fig .3A, B). This evidence concerns the gene CHDH and hepatocellular carcinoma.