The secretion of one of them can affect the behavior of other in the same direction; for example, adipocytes secrete bone morphogenic protein-2 (BMP2) during the phases of late down-regulation and early resting, which help the latent condition in the bulge region, while release of BMP2 was lowered at the end of the resting phase with the stimulation of HF-MSCs (Yi 2017). The gene discussed is BMP2; the disease is hydrops fetalis.