FTLD-CBD cases had a higher burden of CD68-positive microglia in the frontal lobe compared with FTLD-MAPT cases and in TW compared with FTLD-PSP cases (Fig. 5g) but had a similar burden of CR3/43- and Iba1-positive microglia to other FTLD-tau subtypes (Fig. 5h, i). This evidence concerns the gene CRIPTO3 and red-green color blindness.