FTLD-CBD cases had a higher burden of CD68-positive microglia in the frontal lobe and TW compared with controls, but a similar burden of CR3/43- and Iba1-positive microglia to controls in all regions, except for TW, where the burden of Iba1-positive microglia was higher than controls (Fig. 5g–i). The gene discussed is CRIPTO3; the disease is red-green color blindness.