The T3SS activity of B. bronchiseptica complex I strains was reported to alter dendritic cell maturation, enhance the production of the anti-inflammatory cytokine interleukin-10 (IL-10), suppress antigen-specific IFN-γ production during infection and to hinder the development of anti-Bordetella serum antibody levels [15–19]. The gene discussed is IL10; the disease is infection.