In the multivariable logistic regression model (Table 3) older age (Relative Risk [RR] 1.06 [95% confidence interval (CI) 1.04–1.09] per 1 year increase, p < 0.001), COPD (RR 1.82 [95% CI 1.13–2.35]), diabetes (RR 1.56 [95% CI 1.06–2.02]), higher levels of CRP (RR 1.70 [95% CI 1.36–2.07] per standard deviation increase, p < 0.001) and higher concentrations of LDH (RR 2.14 [95% CI 1.65–2.68] per standard deviation increase, p < 0.001) were independently associated with in-hospital mortality, whereas sex, CKD, CVD and hypertension were not. This evidence concerns the gene CRP and chronic obstructive pulmonary disease.