In particular, an association between the sympathetic nervous system hormone adrenaline and IL-6 is found in conditions with increased COVID-19 mortality and underlying chronic diseases disproportionately found among African Americans, including cardiovascular disease,20 diabetes,21 and hypertension.22 Novel or unique stressors, as may be experienced during a pandemic, can lead to exaggerated sympathetic responses.23 Therefore, there may be a key reason to examine a role for psychosocial factors related to African Americans during this pandemic. This evidence concerns the gene IL6 and COVID-19.