The notable absence of alpha‐synuclein pathology helps to differentiate BPAN from other neurodegenerative disorders with brain iron accumulation, particularly phospholipase A2 group VI‐associated neurodegeneration and mitochondrial membrane protein associated neurodegeneration, while tau anatomic distribution is quite distinct from that seen in Alzheimer's disease (AD).7 The gene discussed is MAPT; the disease is neurodegeneration with brain iron accumulation 5.