We did not observe any significant difference in the frequency of total B cells (CD19+) or total IL10-secreting B cells (IL10+CD19+) between T1D patients and controls (14 ± 6.6 and 6.9 ± 3.6 in T1D patients vs. 9.7 ± 2.1 and 8.6 ± 2.9 in controls for B cells and IL10-secreting B cells, respectively). This evidence concerns the gene IL10 and type 1 diabetes mellitus.