Our study clearly confirmed that miR-155-5p, miR-146a-3p, miR-125b-1-3p, and miR-21-3p are associated with IBD, and their correlations with CDH1 expression deserve special attention suggesting the involvement of epithelial to mesenchymal transition (EMT) in CD development, but not in UC. The gene discussed is CDH1; the disease is inflammatory bowel disease.