Based on the analysis and validation of the overall survival rate, we obtained eight prognostic biomarkers associated with BC, including 2 lncRNAs (LINC00466, LINC00460), 1 miRNAs (Hsa-mir-204), and 5 mRNAs (TGFBR2, CDH2, CHRDL1, FGF2, and CHL1). The gene discussed is CDH2; the disease is breast cancer.