Similarly to NCFs, we detected AREG on both control and TGFβ-treated CRC-F-derived EVs by flow cytometry (Figure 8A) and these EVs restored the proportion of KI67 + CRC cells in EGF-dependent organoids in the absence of exogenously added EGF family members (Figures 8B,C). This evidence concerns the gene AREG and colorectal carcinoma.