Multiple logistic regression analysis with backward selection on the discovery cohort showed that elevated levels of MRP8/14 (log10 OR = 7.7, 95% CI = 3.2–18.5) and CRP (log10 OR = 5.1, 95% CI = 1.7–14.7) were predictive for acute KD over an infection (p < 0.001). The gene discussed is S100A8; the disease is infection.