The COPD with the PE group had significantly lower RBC, Hb, HCT, PLT, platelet crit (PCT) (%), eosinophil (EO) (%), lymphocyte (LYM) (%), oxygen saturation (SO2) (%), partial pressure of oxygen (PO2), and fibrinogen (FIB) and higher MPV, neutrophil (NEUT) (%), lactate (Lac), and prothrombin time (PT) than the control group. Here, F2 is linked to chronic obstructive pulmonary disease.