NFKB1 and myocardial infarction: Furthermore, in the in vivo myocardial I/R model, increased myocardial infarction size (Figure 1(c)) was accompanied by upregulation of miR-181c-5p (Figure 1(d)) and enhanced NFκB activity (Figure 1(e)), suggesting that miR-181c-5p may be involved in the NFκB-mediated proinflammatory responses of cardiomyocytes during the pathology of myocardial I/R injury.