In HIV-positive individuals, it has also been observed that the low CD4+ count, high HIV viral load, non-availability or non-usage of highly active antiretroviral therapy (HAART) and the type of antiretroviral (ARV) medication have been explored as possible factors that influence oral Candida carriage as well as with oral candidiasis in HIV patients [10, 11]. The gene discussed is CD4; the disease is oral candidiasis.