DICER1 and cancer: Indeed, autophagy activation by serum starvation or mTOR inhibitor rapamycin decreases Dicer and Argonaute-2 levels, whereas autophagy blockade by inhibitors of lysosomal acidification (bafilomycin A1 or chloroquine) increases their levels in a broad range of cancer cell lines like HeLa cells, MDA-231, T47D, and MDA-435.