In NCBI database ‘’genetic testing registry’’ 38 genes are listed for colorectal cancer detection in 94 tests: ABCB11, APC, ATF7B, AXIN1, BMP2, CASP8, CCR5, CTNNB1, F5, FAH, G6PC, GPC3, GPC4, H19, HFE, HMBS, IFNAR2, IFN6, IFNGR1, IFNL3, IGF2, IGF2R, IL10RB, JAG1, JAK2, MET, MPV17, PDGFRL, PIK3CA, PTPRC, RSS, SERPINA1, SLC25A13, SLC37A4, SPRTN, TJP2, TP53, UROD, (https://www.ncbi.nlm.nih.gov/gtr/). This evidence concerns the gene PIK3CA and colorectal cancer.