HMOX1 and cancer: Further, the enrichment analysis identified the modulation of 54 different pathways in which pathways in cancer was majorly modulated by regulating 12 genes (AR, CASP8, CDK4, CTNNB1, EPAS1, HMOX1, KLK3, MMP2, NFE2L2, NOS2, RAC1, and RARA) under the background of 515 proteins at the false discovery rate of 7.71E−08.