As shown in Table 5, we detected higher levels of TNF-α, IL-10 and GM-CSF in CSF of paraneoplastic anti-NMDARE patients compared to the negative symptom control group (P < 0.05)and lower level of IL-1α and VEGF-A compared to the anti-NMDAR encephalitis patients(P < 0.05). The gene discussed is TNF; the disease is encephalitis.