We observed BRAF p.V600E in 2 cases and found no other specific molecular alteration except for one hotspot ACVR1 p. G328V mutation, mostly described in “diffuse intrinsic pontine glioma” (DIPG) [23] and in one case of pediatric spinal glioblastoma in the literature [28]. The gene discussed is BRAF; the disease is diffuse intrinsic pontine glioma.