DUSP6 and glioblastoma: Quantitative transcriptional analysis of DUSP6 was assessed by RT-qPCR measuring high mRNA levels in a panel of twenty primary glioblastomas (GBM, WHO grade 4) (Fig. 1b) by quantifying the mRNA fold-induction over Normal Human Astrocytes (NHA) and Neural Stem Cells (NSC) which specify distinct glioblastoma subtype [17–20].