Just like in our study, we observed that BRD4 inhibitor JQ1 or knockdown of BRD4 specifically diminished the mRNA and protein levels of tumor suppressor RCAN1.4 in a time- and dose-dependent manner, which at least in part explains why JQ1 could not achieve good anti-tumour effects in solid tumours. This evidence concerns the gene BRD4 and neoplasm.