Adjustments for age, sex (female vs. male), obese (yes vs. no), diabetes mellitus (yes vs. no), atrial fibrillation (yes vs. no), previous CVD events (yes vs. no), NHISS, stroke syndrome (TACS vs. other), stroke subtype (Cardioembolic vs. other), acute treatment (no vs. yes), serum glucose, CRP, eGFR, copeptin and NT-ProBNP, per one-unit(μg/mL) increase in adiponectin, the risk of MACCE increased by 13% (HR, 1.13; 95%CI 1.06–1.19), Table 3. The gene discussed is AVP; the disease is diabetes mellitus.