Moreover, gain‐of‐function mutations in NLRP3 cause autosomal dominantly inherited autoinflammatory diseases that are collectively named Cryopyrin‐Associated Periodic Syndrome (CAPS), and which comprise—in increasing order of clinical severity—familial cold‐induced autoinflammatory syndrome (FCAS), Muckle‐Wells syndrome (MWS), and neonatal‐onset multisystem inflammatory disease (NOMID) (also known as chronic infantile neurologic, cutaneous, articular syndrome (CINCA)). Here, NLRP3 is linked to CINCA syndrome.