In addition, there was a significant association between CMTM6 and tumoral PD-L1 expression in these two subtypes but no significant association between CMTM6 and inflammatory cell PD-L1 expression in non-MTM subtypes, suggesting that high CMTM6 activity in HCC contributes to tumoral PD-L1 expression. The gene discussed is CMTM6; the disease is hepatocellular carcinoma.