Clinical trials found that,[20] Kebimin Spray can significantly decrease the serum IgE high values of different level in the patients with allergic rhinitis, mainly because that Fu Zi (Radix Aconiti Lateralis Preparata) in Kebimin Spray has adrenocorticoid-like effect, to reduce serum IgE produce, prevent being combined with target cells, to make eosinophils and mast cells in “sleep” state, to cause the loss of internal conditions for the formation of allergic rhinitis. This evidence concerns the gene IGHE and allergic rhinitis.