Laboratory features comprehend cytopenias, elevated CRP, coagulation abnormalities (hypofibrinogenemia, elevated D-dimer, prolonged prothrombin and partial thromboplastin time), evidence of hepatocellular injury, high levels of triglycerides and ferrritin, and hemophagocytosis (ie, phagocytosis by tissue-resident macrophages [histiocytes] of erythrocytes, leukocytes, platelets, and their precursors) on biopsy of bone marrow and other tissues.[1] Signs of organ failure can appear in the advanced stages of the syndrome. This evidence concerns the gene F2 and Hypofibrinogenemia.