Based on considering the differentially expressed genes with an absolute fold‐change > 3, P < 0.05, and reported previously as known oncogenes with high expression in various tumors, including GC [12, 13, 14, 15, 16], four cancer‐associated genes including MAP2, MDM2, MAPKBP1, and GPNMB were selected as candidates to be investigated. This evidence concerns the gene GPNMB and cancer.