FBXO7 and hereditary spastic paraplegia: FBXO7 deficiency is a rare genetic condition described in 26 patients from 10 unrelated families, giving three major phenotypes: autosomal recessive juvenile‐onset levodopa responsive PPS (14 patients), SPG (7 patients), and isolated parkinsonism (5 patients).2, 3, 4, 5, 6, 7, 8, 9