Notably, individuals with Basal and Luminal A breast cancer areclearly separated in the first two dimensions and tend to respectively havepositive and negative loadings in the first dimension of the MFA; Luminal B andNormal-like subtypes largely overlap with the Luminal A subtype for thispathway, while Her2 is located intermediate to the Luminal and Basal subtypes,as could be anticipated due to the equal prevalence of Her2 amplification inboth Luminal and Basal subtypes. The gene discussed is ERBB2; the disease is breast cancer.