CXCR4 and myocardial ischemia: Other studies are consistent with CXCL12-CXCR4 cardioprotection during pre- and post-myocardial ischemia, which is prevented by AMD3100 or a CXCR4 inducible knockout in cardiac myocytes (Hu et al., 2007; Huang et al., 2011; Dong et al., 2012; LaRocca et al., 2019).