The comparison of cytokines profile from secretome of AD-MSC (one of the most MSC type used in clinical trials) and of hUCESC shows that the latter has higher levels of cytokines with recognized effect in regenerative (TIMP-1, TIMP-2, FGF-6, FGF-7, uPAR, and HGF) (Bermudez et al., 2015; Sendon-Lago et al., 2019), anti-tumoral (FLT-3 ligand, LAP, LIGHT, and IP-10) (Eiró et al., 2014), and anti-inflammatory (IL-13 and NT-3) (Eiró et al., 2014; Bermudez et al., 2016) processes. Here, TNFSF14 is linked to Alzheimer disease.