TGFA and Alzheimer disease: Thus, for example, it has been showed that AD-MSC secreted higher amounts of pro-angiogenic molecules (matrix metalloproteinases (MMPs) (Amable et al., 2014) or VEGF (Hsiao et al., 2012), compared with other MSC, such as BM-MSC; whereas UC-MSC secreted high levels of immunomodulatory factors, such as IL-6, -7 and -10, PDGF-AA and TGF-α (Amable et al., 2014).