IL6 and colitis: IL-6, IL-17, IL-23, and RORγt were determined by qRT-PCR, and significant differences were observed in the expression levels of all these mRNA when comparing the TNBS-induced colitis groups with the healthy control group, while the addition of thalidomide downregulated their mRNA expression (p < 0.05, as compared with the untreated TNBS-induced colitis group, Figure 8).