MGMT and glioblastoma: In MGMT unmethylated glioblastoma, we only observed a longer overall survival in residual CE volumes of 0–1 cm3 (427 days; 95% CI, 350–503), when compared to 1–5cm3 (299 days; 95% CI, 270–327; p = 0.006) or to >5 cm3 (200 days; 95% CI, 102–298; p = 0.003) (Figure 1C).