MGMT and neoplasm: Kaplan Meier estimates suggested that the impact of maximal CE tumor resection was more beneficial for patients with MGMT methylated glioblastoma and that it significantly improved median overall survival (572 days; 95% CI, 424–720), when compared to STR (342 days; 95% CI, 282–402; p = 0.014) or biopsy (112 days; 95% CI, 36–42; p = 0.001) (Figure 1A).