HK2 and colonic neoplasm: Given the consequent results that miR-125b-5p was apparently negatively associated with cisplatin resistance in colon cancer, both our in vitro and in vivo data consistently elucidated a DANCR–miR-125b-5p/HK2 axis in the acquired cisplatin resistance, suggesting targeting this molecular pathway contributes to develop therapeutic approaches against chemoresistance of colon cancer.