Zhang found that patients with laryngeal squamous cell carcinoma (LSCC) with advanced tumor node metastasis (TNM) stages, poorly differentiated tumors, lymph node metastases, and poor prognosis had high CDR1as levels but low miR-7 levels, and CDR1as promoted the tumor progression by inhibiting miR-7 function and upregulating the expression of miR-7 target genes, including the proliferation indices ki-67, CCNE1, and PIK3CD [55]. The gene discussed is MKI67; the disease is neoplasm.