Moreover, Yang demonstrated faster tumor growth in the CDR1as + miR-7 mimic group than in the miR-7 mimic group, and that CDR1as may regulate chemosensitivity in 5-FU-resistant BC cells by inhibiting miR-7 to regulate the miR-7 target gene cyclin E1(CCNE1) [53]. Here, CCNE1 is linked to breast cancer.