As shown in Figure 6, the TBARS, protein carbonyl contents, and MPO activity in the diaphragm were increased significantly in rats in the sepsis group compared to rats in the sham group 24 h after surgery (P < 0.01), while the increase was partially restored after NRG-1β treatment (P < 0.01, P < 0.05). The gene discussed is MPO; the disease is Sepsis.