CCL4 and metabolic dysfunction-associated steatohepatitis: In human NASH patients, hepatic CXCL9, CXCL10, CXCL11, CCL3, CCL4, and CCL5 levels were markedly higher than that of the healthy controls and the level of circulating CXCL10 was correlated with the severity of lobular inflammation (74, 75).