PRDM1 and systemic lupus erythematosus: Monocyte derived-dendritic cells (MO-DCs), but not B cells derived from healthy female individuals with the rs548234 SNP, which is a risk factor for SLE, show a lower level of PRDM1 expression, suggesting that a proper expression of PRDM1 in dendritic cells (DCs) is required for immunological homeostasis in a gender-specific manner (11).