TGM2 and glioblastoma: Analysis of reverse-phase protein array data (RPPA; a high-throughput antibody-based technique) from the TCGA GBM dataset yielded proteins significantly associated with TREM1, including IFGBP2, TGM2 VEGFR2, and NDRG1, many of which have also been linked to hypoxia (Figures 5B,G–I).