Studying vesicles released from RAW264.7 cells 24 h post-infection, authors described that the pool of the so called “exosomes” sedimented at 100,000 g and previously described as containing mycobacterial envelope components encloses two vesicle sub-populations that can be separated on continuous sucrose gradient, (i) vesicles carrying the LAM and LM but devoid of ones of the exosomal markers CD9 and CD63 and inversely (ii) vesicles bearing the CD9, CD63, and CMH-II host proteins but devoid of LAM and LM (52). The gene discussed is CD9; the disease is infection.