However, we found that gpi7 mutant vaccination could significantly increase the levels of TH2-type effector cytokines, such as IL-4 and IL-13, in the spleen and serum of mice when challenged by C. albicans SC5314, which suggests that these play a role in the immunoprotection against candidiasis (Figure 7B). The gene discussed is PIGG; the disease is Candidiasis, Invasive.