Finally, in glioblastoma, the lncRNA XIST was revealed to regulate glucose metabolism by targeting GLUT1 and GLUT3 through the miR-126-dependent insulin receptor substrate 1 (IRS1)/PI3K/Akt pathway and to positively control glioblastoma cell growth in vivo and in vitro (117). This evidence concerns the gene XIST and glioblastoma.