HK2 and urinary bladder cancer: Another lncRNA of the UCA1 gene, which was highly expressed in bladder carcinoma and enhanced the tumorigenic behavior of bladder cancer cells in vitro and in vivo (135, 136), promoted glycolysis through the mTOR-STAT3/microRNA143 pathway in bladder cancer cells, and UCA1-induced HK-2 was shown to be an important mediator in this process (130).