KLRC1 and myeloid sarcoma: Interestingly, NK cell regulatory activity has been demonstrated in several autoimmune diseases, such as multiple sclerosis (MS), experimental colitis or encephalitis (EE) and arthritis (RA), by different strategies such as cytokine release, interaction with ligands of the receptors NKG2D, NKG2A, NKp46 or perforin-mediated T cell death (63, 72, 73).