Ding et al. (2008a, b) identified two voltage-gated K+ channels, Eag1 (KV10.1, KCNH1) and hERG1 (KV11.1, KCNH2), which are aberrantly expressed in ESCC and are correlated with poor prognosis (Ding et al., 2008a, b). The gene discussed is KCNH2; the disease is esophageal squamous cell carcinoma.