IFNA1 and COVID-19: Chan et al. (2015) found that the LPV/r plus IFN combination resulted in better clinical scores, decreased weight reduction, less pulmonary infiltrates, and lower viral load in marmosets inoculated with MERS-CoV, compared with controls. Recently, a randomized controlled study observed that the early use of a combination of IFN, LPV/r, and RBV was effective for the treatment of COVID-19, compared with LPV/r alone (Hung et al., 2020).