Therefore, (+)-JQ1 has been extensively used as a powerful pharmacological tool to study the biological functions of the BET family in various diseases, such as leukemia, osteosarcoma, gallbladder cancer, colon cancer, and tumor angiogenesis (Zuber et al., 2011; Hu et al., 2015; Lee et al., 2015; Bid and Kerk, 2016; Bid et al., 2016; Hao et al., 2017). The gene discussed is DNER; the disease is neoplasm.