MAPT and Alzheimer disease: The increased tau immunoreactivity in plaque-associated dystrophic neurites was not detected by the anti-human tau antibody (Figures 1C–E) in 5XFAD-AD injected mice (Figures 1C–E) indicating that this increased tau immunoreactivity was not due to the accumulation of human tau (injected 3 months before) in the dystrophic neurites surrounding plaques.