CD274 and metastatic malignant neoplasm in the lymph nodes: Among ADC patients (Table 2), PD-L1 positivity was significantly more frequent in male patients (p=0.027), smokers (p=0.027), stage II/III/IV patients (p=0.008), patients with lymph node metastasis (p < 0.0001), carriers of wild-type EGFR (p=0.004), and at higher SUVmax values (p < 0.0001).