Overall, CT2A and Mut3 tumor types have higher frequencies of inhibitory and exhausted immune cells in the tumor microenvironment with CT2A showing fewer total T cells, high levels of CD39, fewer activated microglia and exhausted CD8 T cells, while Mut3 had fewer CD4/CD8 T cells characterized by higher frequency of regulatory CD4 T cells and fewer type A DCs. Here, CD4 is linked to neoplasm.